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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8L2
All Species:
3.94
Human Site:
S449
Identified Species:
12.38
UniProt:
Q9H6S3
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6S3
NP_073609.2
715
80621
S449
S
A
P
I
E
E
V
S
P
V
S
R
Q
S
I
Chimpanzee
Pan troglodytes
XP_512904
745
82543
Q480
D
P
V
E
K
Q
L
Q
H
E
R
R
R
W
Q
Rhesus Macaque
Macaca mulatta
XP_001116697
615
68955
F378
A
E
L
V
H
F
L
F
G
P
L
D
L
I
V
Dog
Lupus familis
XP_534881
791
88639
P457
S
S
V
S
E
Y
P
P
A
D
G
Y
A
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99K30
729
82211
T452
S
V
P
S
D
Q
L
T
P
K
N
R
L
S
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510664
556
62861
A319
N
C
P
E
R
N
L
A
V
S
V
V
I
P
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666818
677
76506
S437
M
P
K
S
P
V
Q
S
E
Y
R
S
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785396
970
107261
P685
I
G
H
S
H
G
P
P
T
H
T
N
G
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.2
79.7
42.5
N.A.
84
N.A.
N.A.
29
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
58.2
80.8
60.1
N.A.
90.1
N.A.
N.A.
46.1
N.A.
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
6.6
0
13.3
N.A.
33.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
26.6
20
N.A.
73.3
N.A.
N.A.
33.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
0
0
0
0
0
13
13
0
0
0
13
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
13
0
0
0
0
13
0
13
0
0
0
% D
% Glu:
0
13
0
25
25
13
0
0
13
13
0
0
0
13
0
% E
% Phe:
0
0
0
0
0
13
0
13
0
0
0
0
0
13
13
% F
% Gly:
0
13
0
0
0
13
0
0
13
0
13
0
13
0
13
% G
% His:
0
0
13
0
25
0
0
0
13
13
0
0
0
0
0
% H
% Ile:
13
0
0
13
0
0
0
0
0
0
0
0
13
13
13
% I
% Lys:
0
0
13
0
13
0
0
0
0
13
0
0
13
0
0
% K
% Leu:
0
0
13
0
0
0
50
0
0
0
13
0
25
0
13
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
13
0
0
0
0
13
13
0
13
13
% N
% Pro:
0
25
38
0
13
0
25
25
25
13
0
0
0
13
0
% P
% Gln:
0
0
0
0
0
25
13
13
0
0
0
0
13
0
13
% Q
% Arg:
0
0
0
0
13
0
0
0
0
0
25
38
13
0
0
% R
% Ser:
38
13
0
50
0
0
0
25
0
13
13
13
0
25
0
% S
% Thr:
0
0
0
0
0
0
0
13
13
0
13
0
0
0
0
% T
% Val:
0
13
25
13
0
13
13
0
13
13
13
13
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
13
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _